The occurrence of mountain sickness is not related to whether the pre-departure training is sufficient or not, and whether the condition of physical fitness under the mountain is good or bad.
We can illustrate this argument from two aspects, drug conditions and alpine physiology. Under the following three conditions, prevention of mountain sickness can be prevented with DIAMEX: (Note 1)
1. Within a day, passive (such as by plane or ride) quickly rises to 3000 meters.
2. Rapidly rise in height in almost sleeping conditions, such as up to 1000 meters in a day, which usually occurs when climbers are subjected to special terrain restrictions or artificial violence. A hiking climber, under a sound plan, will not happen.
3. Previously had a history of mountain sickness. (Dose slightly ...)
Why can't we see "poorer physical fitness" or "undertraining" in the adaptation criteria of medication?
Let us take the occurrence of high altitude pulmonary edema (HAPE) as an example:
The lungs are the organs we use to change air. At high altitudes, the partial pressure of oxygen decreases because of the decrease in atmospheric pressure, and the oxygen concentration in the blood also decreases, even reaching concentrations that cause tissue hypoxia.
Fortunately, there is a natural regulation system in the human body.
In hypoxic tissue, in order to preserve the blood flow of vital organs, the blood vessels of the brain will expand and the peripheral blood vessels will contract, allowing most of the blood to perfuse vital organs.
But this is not enough, because the normal human lung in the embryonic development period, some parts of the congenital development is relatively good, some parts of the congenital development is relatively poor. This, under the atmospheric pressure of the flat ground, the partial pressure of oxygen is high and does not have much influence on the quality of the ventilation of the whole lung.
However, at high altitudes, the partial pressure of oxygen is lower, and the poorly developed part of the body under this condition will have worse gas exchange efficiency. As a result, the oxygenated blood with poor oxygen concentration after the ventilation process and the oxygenated blood with high oxygen concentration processed through the lungs with high ventilation efficiency will return to the left heart. Before mixing, the overall oxygen concentration is diluted.
Therefore, another way for the body to cope with anoxic conditions is to contract some of the blood vessels in the lungs and retain the blood for those parts of the body that have better development of ventilation. In order to maintain the overall lung oxygen exchange quality.
However, as a result, the blood vessels in the lungs of those parts of the ventilation system will suddenly flow into a large amount of blood, resulting in a rapid increase in pulmonary artery pressure. In severe cases, the alveolar microvessels in the place where the ventilation occurs will be damaged. Mechanical, because the upstream pressure is too "broken".
We can observe the microvascular damage in the lung under electron microscope.
Because the microvessels are broken, blood leaks out of the blood vessels and leaks into the alveoli, resulting in a good part of the alveoli that is also leaking from the blood vessels, impairing ventilation efficiency, causing tissue hypoxia, and high altitude pulmonary edema. Symptoms and fatal consequences arise from delirium.
There is a saying that it is very clear that patients with high-altitude pulmonary edema are drowned by the water in their own bodies. This phenomenon can be observed in an indirect way, such as chest x-rays. At this time, the observed phenomenon is similar to pulmonary edema. Even in the hospital's respiratory care center, patients with high-altitude pulmonary edema usually need to be treated against the acute respiratory distress syndrome (ARDS).
When high-elevation pulmonary edema occurs, DESCENT IS URGENT - as soon as possible!! (Note 2).
Therefore, we can use a slow rise to allow the blood vessels of the lungs to gradually adapt to high pressure, or to use a descending height to reduce the blood pressure of the lungs to prevent or treat alpine pulmonary edema.
Therefore, even before it reaches the mountain, even a physically well-trained long-distance runner will not be aware of his pulmonary vascular conditions. Whether or not he will develop severe alpine disease after going uphill is even more unknown. After all, physical fitness training is a method. However, this does not change the inborn condition. Therefore, his effect should be unquestionable and helpful in improving physical fitness. In the prevention of mountain sickness, I think we must still doubt it.
The reason why the aborigines of high mountains are fierce is that they live in the mountains for a long time and the heme has been more than plain people, so the symptoms of the mountains will be less visible. However, if they are told to climb sharply toward higher altitudes, I believe they will also have alpine disease.
I am not a mountaineering expert. In terms of the actual experience in the mountains and the mountains, it may be more clear that you may ask advanced on-line mountain climbing.
References:
Note 1: Taken from http://AMS-medical.html
Note 2: The reference material is the same as note one.
This article is reprinted to: Maxwell BBS Station, Taiwan University (and authorized by the original author)
Author: Wang Shihao (Taizhong Veterans General Hospital / former Chairman of Mountaineering, China Academy of Medicine)
We can illustrate this argument from two aspects, drug conditions and alpine physiology. Under the following three conditions, prevention of mountain sickness can be prevented with DIAMEX: (Note 1)
1. Within a day, passive (such as by plane or ride) quickly rises to 3000 meters.
2. Rapidly rise in height in almost sleeping conditions, such as up to 1000 meters in a day, which usually occurs when climbers are subjected to special terrain restrictions or artificial violence. A hiking climber, under a sound plan, will not happen.
3. Previously had a history of mountain sickness. (Dose slightly ...)
Why can't we see "poorer physical fitness" or "undertraining" in the adaptation criteria of medication?
Let us take the occurrence of high altitude pulmonary edema (HAPE) as an example:
The lungs are the organs we use to change air. At high altitudes, the partial pressure of oxygen decreases because of the decrease in atmospheric pressure, and the oxygen concentration in the blood also decreases, even reaching concentrations that cause tissue hypoxia.
Fortunately, there is a natural regulation system in the human body.
In hypoxic tissue, in order to preserve the blood flow of vital organs, the blood vessels of the brain will expand and the peripheral blood vessels will contract, allowing most of the blood to perfuse vital organs.
But this is not enough, because the normal human lung in the embryonic development period, some parts of the congenital development is relatively good, some parts of the congenital development is relatively poor. This, under the atmospheric pressure of the flat ground, the partial pressure of oxygen is high and does not have much influence on the quality of the ventilation of the whole lung.
However, at high altitudes, the partial pressure of oxygen is lower, and the poorly developed part of the body under this condition will have worse gas exchange efficiency. As a result, the oxygenated blood with poor oxygen concentration after the ventilation process and the oxygenated blood with high oxygen concentration processed through the lungs with high ventilation efficiency will return to the left heart. Before mixing, the overall oxygen concentration is diluted.
Therefore, another way for the body to cope with anoxic conditions is to contract some of the blood vessels in the lungs and retain the blood for those parts of the body that have better development of ventilation. In order to maintain the overall lung oxygen exchange quality.
However, as a result, the blood vessels in the lungs of those parts of the ventilation system will suddenly flow into a large amount of blood, resulting in a rapid increase in pulmonary artery pressure. In severe cases, the alveolar microvessels in the place where the ventilation occurs will be damaged. Mechanical, because the upstream pressure is too "broken".
We can observe the microvascular damage in the lung under electron microscope.
Because the microvessels are broken, blood leaks out of the blood vessels and leaks into the alveoli, resulting in a good part of the alveoli that is also leaking from the blood vessels, impairing ventilation efficiency, causing tissue hypoxia, and high altitude pulmonary edema. Symptoms and fatal consequences arise from delirium.
There is a saying that it is very clear that patients with high-altitude pulmonary edema are drowned by the water in their own bodies. This phenomenon can be observed in an indirect way, such as chest x-rays. At this time, the observed phenomenon is similar to pulmonary edema. Even in the hospital's respiratory care center, patients with high-altitude pulmonary edema usually need to be treated against the acute respiratory distress syndrome (ARDS).
When high-elevation pulmonary edema occurs, DESCENT IS URGENT - as soon as possible!! (Note 2).
Therefore, we can use a slow rise to allow the blood vessels of the lungs to gradually adapt to high pressure, or to use a descending height to reduce the blood pressure of the lungs to prevent or treat alpine pulmonary edema.
Therefore, even before it reaches the mountain, even a physically well-trained long-distance runner will not be aware of his pulmonary vascular conditions. Whether or not he will develop severe alpine disease after going uphill is even more unknown. After all, physical fitness training is a method. However, this does not change the inborn condition. Therefore, his effect should be unquestionable and helpful in improving physical fitness. In the prevention of mountain sickness, I think we must still doubt it.
The reason why the aborigines of high mountains are fierce is that they live in the mountains for a long time and the heme has been more than plain people, so the symptoms of the mountains will be less visible. However, if they are told to climb sharply toward higher altitudes, I believe they will also have alpine disease.
I am not a mountaineering expert. In terms of the actual experience in the mountains and the mountains, it may be more clear that you may ask advanced on-line mountain climbing.
References:
Note 1: Taken from http://AMS-medical.html
Note 2: The reference material is the same as note one.
This article is reprinted to: Maxwell BBS Station, Taiwan University (and authorized by the original author)
Author: Wang Shihao (Taizhong Veterans General Hospital / former Chairman of Mountaineering, China Academy of Medicine)
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